Genetic Susceptibility in MAlignant Pleural Mesothelioma: Clinical Implication of GermliNE VariaTionS (MAGNETS)

March 28, 2025

Primary Outcome Measures

the comparison of prevalence of germline mutations in MPM patients vs asbestos exposed healthy subjects

Secondary Outcome Measures

Secondary aim will be the comparison of overall survival (OS) according to mutational status in MPM patients.

Inclusion Criteria

Inclusion Criteria Cohort A:

Patient with a documented diagnosis of MPM (any disease stage and independently from chemo line treatment)
Age ≥ 18 years (there is no upper age limit).
Patient who gives their informed consent to participate in the study

Inclusion Criteria Cohort B:

Former asbestos exposed healthy subjects
Age ≥ 18 years (there is no upper age limit).
Subject who gives their informed consent to participate in the study

Exclusion Criteria

Exclusion Criteria Cohort A:

No exclusion criteria

Exclusion Criteria Cohort B:

No exclusion criteria

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