Mesothelioma
Canada is creating new rules for asbestos abatement. The government in British Columbia is going to require that companies that perform asbestos abatement have licenses issued by the government for them to operate. The Canadian workers’ compensation statutory agency WorkSafeBC is creating the requirements for companies to be fully licensed to safely remove asbestos. Asbestos…
Mesothelioma could soon be diagnosed by blood test. Researchers in China have found a new method to analyze blood samples of people with mesothelioma. The researchers used gas chromatography-mass spectrometry (GC-MS). The hope was that the researchers would find biomarkers in the blood of mesothelioma patients that could help with diagnosis of the cancer. Mesothelioma…
Finding Out How Asbestos Causes Mesothelioma Researchers are finding out why it takes a long time for mesothelioma to develop. A study in the Journal of Environmental Research found that the immune system sensing and interacting with particles changes how mesothelioma develops in the body. Researchers found that the main reason mesothelioma is caused by…
Researchers are trying to find out if mesothelioma can be prevented. Mesothelioma is a cancer of the lining of certain areas of the body including the lungs, abdomen, heart, and testicles. After asbestos exposure, some people develop mesothelioma over a period of many years. Asbestos fibers become lodged in the mesothelium which then causes DNA…
An Indiana warehouse fire led to asbestos contaminated debris falling onto the surrounding community. The debris landed on school yards, playgrounds, day cares, and private homes. Areas affected by the falling debris include Richmond, Indiana, and nearby areas in Ohio. Asbestos fibers are weightless, so smoke carried the fibers, which then fell to the ground…
Researchers from China tried to determine whether immunotherapy or chemotherapy is better as a second line treatment option for relapsed pleural mesothelioma. There is no current standard therapy for people whose mesothelioma comes back, which makes it hard for doctors to make treatment decisions for patients. Mesothelioma is very aggressive, and no treatments are available…
Primary Outcome Measures Rate of patients who decide to enroll in a mesothelioma medical study. [ Time Frame: 3 months ] Number of mesothelioma patients who remain in clinical trial until completion. [ Time Frame: 12 months ] Inclusion Criteria Must have a medical diagnosis of mesothelioma that has been confirmed by a physician. Aged ≥ 18 years old and ability to provide…
A YAP/TEAD inhibitor is showing promising results for people with mesothelioma and other cancers. The inhibitor, known as VT3989, was well tolerated and had good anti-tumor effects in cancer patients with mesothelioma and NF2 mutations. Results were recently published from the first human study. Seven of 69 patients had radiological partial responses, which includes tumor…
Primary Outcome Measures Phase 1 (Dose Escalation): Incidence of adverse events [ Time Frame: From CTX131 infusion up to 28 days post-infusion ] Defined as dose-limiting toxicities Phase 2 (Cohort Expansion): Objective response rate (ORR) [ Time Frame: From CTX131 infusion up to 60 months post-infusion ] ORR based on Independent Review Committee (IRC) assessment, defined as the proportion of subjects who have…
Researchers decided to look at the relationship between having mesothelioma in addition to a second cancer and their impact on survival. Researchers found that a second cancer did not affect survival for most patients with mesothelioma, but for patients with a specific type of mesothelioma, survival was affected. Mesothelioma is a rare and aggressive cancer…
