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A new study looking at low dose radiation and immunotherapy is showing promising results for non-small cell lung cancer. Patients treated with the combination had higher progression free survival compared to patients who received immunotherapy alone. Research was completed at Weill Cornell Medicine, NewYork-Presbyterian as well as at Columbia University Vagelos College of Physicians and…
Primary Outcome Measures Number of Patients with Dose Limiting Toxicity Secondary Outcome Measures Percent of Patients with best response as either complete remission or partial remission. Median γδT cell persistence Inclusion Criteria 1. Patients with advanced cancer that expresses GPC3 or Mesothelin protein; 2. Life expectancy >12 weeks; 3. Adequate heart, lung, liver, kidney, and…
Polaris Group recently announced an application for a rolling submission of a new mesothelioma treatment. The Biologic License Application is the first step in becoming approved by the Food and Drug Administration. The treatment, known as ADI-PEG 20, is for the use on non-epithelioid mesothelioma patients alongside pemetrexed and platinum chemotherapy. The non-epithelioid subtypes of…
Primary Outcome Measures Primary endpoint – To evaluate the activity of neo-adjuvant treatment by the determination of pathological complete response rate (pCR) Secondary Outcome Measures Secondary endpoint – To further evaluate the activity of neo-adjuvant treatment in terms of major pathological response. Secondary endpoint – To further evaluate the activity of neo-adjuvant treatment in terms…
The Center for Asbestos Related Disease is working on new research articles that will be released throughout this year. They will be focusing on asbestos and autoimmune disease. The articles will show results from analyzing the health impact of exposure to amphibole asbestos from Libby, Montana. It can take less exposure to amphibole asbestos fibers…
Pleural mesothelioma, a cancer mainly caused by asbestos, is a hard cancer to treat. Diagnosis usually occurs when it is in a late stage, leading to limited treatment options. New clinical trials are always being performed to try to find a new treatment approach that could possibly extend the lives of patients or even cure…
Surgery is usually the first choice for patients and doctors for the treatment of early-stage cancer. There are other options though like radiotherapy. A special type of radiotherapy called Carbon-ion radiotherapy (CIRT)has become popular with doctors. A study in Japan showing how the therapy can benefit patients with early-stage lung cancer recently released results. Carbon-ion…
A group of Australian patients receiving Checkmate743 therapy saw higher levels of toxicity compared to CheckMate743 clinical trial patients. Checkmate743 consists of a dual treatment of ipilimumab and nivolumab and is the standard of care for patients with unresectable pleural mesothelioma. Unresectable means patients are not able to receive surgery to remove their cancer. Patients…
A new biomarker has been found for the diagnosis of mesothelioma by scientists in Japan. Information from this research could revolutionize how mesothelioma is diagnosed and treated in the future. Mesothelioma is a hard cancer to diagnose because it shares symptoms with other cancers. Cancers it can look like include squamous cell lung carcinoma and…
Johnson & Johnson may try to file bankruptcy for a third time to address its talc liabilities. The company has failed twice before but is looking again to file for bankruptcy under a different corporate structure. There are around 51,000 lawsuits claiming that people who used Johnson & Johnson’s talc-based products now have cancer because…
