Pemetrexed (Alimta)
Malignant Pleural Mesothelioma (MPM) is a rare, aggressive asbestos –related cancer that has a poor survival rate due to the fact that the cancer is hard to detect early, and once detected, has usually spread and is hard to control. Surgery is typically an effective option for removing cancerous cells, but in some cases, surgery…
Combining different types of treatment when it comes to treating mesothelioma is common because of how aggressive the cancer can be. While some treatments do prove to be effective, the overall prognosis of an individual with this asbestos-related cancer remains dim. A recent study done in Korea carefully evaluated the combination of cisplatin, a common…
Understanding malignant mesothelioma and the way it develops is significant when discovering prevention, development control, and the eventual lead to a cure. Cancer researchers at the Mayo Clinic have been researching the genetic composition of the disease in hopes to find a connection between the development of mesothelioma and mutations in DNA. To find these…
Chemotherapy remains one of the most effective treatments for mesothelioma. Because there is no cure, it works to prolong the lives of patients. Unfortunately, even the most effective methods can become inadequate as treatments continue. A current clinical trial is attempting to extend the usefulness period of chemotherapy and in turn extend the lives of…
A recent mesothelioma study found the addition of bevacizumab to the chemotherapy treatment of pemetrexed plus cisplatin may increase the survival rate in patients. From 2008 to 2014, patients were given the standard treatment in 21-day increments for six cycles, with some receiving bevacizumab. The addition of bevacizumab increased survival to a median of 19.8…
Researchers with the National Cancer Institute recently found an immunotoxin may increase the efficacy of chemotherapy. When combined with popular treatments cisplatin and pemetrexed, SS1P caused antitumor activity in patients. SS1P is an immunotoxin, a protein made by humans with a large targeting section linked to a toxin. Specifically, SS1P was created to attack an…
Scientists around the world work endlessly to discover new treatments for mesothelioma. Taking decades to develop, the asbestos-caused cancer leaves most with less than a year to live after diagnosis. Many studies focus on the effectiveness of current treatments, hoping to expand current knowledge and provide victims with the best possible care and outcome. Recent…
After new evidence surfaced suggesting the enzyme aromatase is associated with malignant mesothelioma, Italian scientists began testing breast cancer drug Aromasin (exemestane) on mice and mesothelioma cells. Designed to inhibit aromatase, Aromasin curbs cell growth in breast cancer patients by helping reduce the amount of estrogen in the body. In the mesothelioma cells and mice,…
For those with inoperable malignant pleural mesothelioma, Alimta (permetrexed) combined with cisplatin remains the top treatment. Japanese researchers recently analyzed the results of 30 patients taking either Gemzar or the Alimta combination and compared complications, disease control and survival rates. Thirty mesothelioma cases were examined featuring 13 patients taking Gemzar and the remaining 17 taking…
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