Posts by Steven Chervenick
Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma
This is a single-arm, open, II phase study to evaluate the safety and efficacy of Toripalimab, pemetrexed and carboplatin in the treatment of locally advanced malignant MPM in 15 newly diagnosed patients with locally advanced malignant MPM.
Read MoreThoracic Chemotherapy After Surgery Could Help Pleural Mesothelioma Patients Survive Longer
Hyperthermic intrathoracic chemotherapy alongside aggressive therapy (HITHOC) could help extend pleural mesothelioma patient survival. Doctors perform this by circulating a heated high concentration chemotherapy solution in the chest cavity for one hour right after aggressive surgery is performed on a patient. They do this to kill microscopic tumor cells that doctors may have missed during…
Read MoreMesothelioma Chemotherapy Resistance Could be Due to Cell Hibernation
Canadian researchers have discovered a cause of chemotherapy resistance in mesothelioma and other cancers. This is great news because this can lead to new treatments being created to combat the incurable cancer. There are other types of treatments approved for mesothelioma, but they might not work and chemotherapy could be the best option. The Canadian…
Read MoreStudy to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 Gene Mutations
Primary Outcome Measures Occurrence of Dose Limiting Toxicity [ Time Frame: over the first 21 days of dosing ] Incidence of Adverse and Serious Adverse Events Occurrence of General Toxicity [ Time Frame: through study completion, an average of 30 months ] Incidence of Adverse and Serious Adverse Events, Discontinuations due to Adverse Events and general safety Evaluations Secondary Outcome Measures Tumor Response…
Read MorePeople with an Inherited Mutation on the BLM Gene Could Be More at Risk of Developing Mesothelioma
New research from the University of Hawaii is showing that the inherited mutation on the BLM gene can increase the chance of getting mesothelioma. The researchers sequenced the DNA of 155 mesothelioma patients. People without the BLM gene were more likely to develop mesothelioma, especially when exposed to carcinogenic asbestos fibers. If people find out…
Read MoreCholesterol Drugs Called Statins Could Help Extend Mesothelioma Sufferers’ Lives
A group of drugs called statins used for controlling cholesterol are showing that they can help mesothelioma patients taking PD-1 inhibitors survive longer. Researchers in Italy and the Netherlands found this information in an international study of 250 patients. The patients studied either had pleural mesothelioma or non-small cell lung cancer. The researchers found that…
Read MoreThe ONCOS-102 Vaccine is Still Showing Promising Results
The ONCOS-102 immunotherapy vaccine is still showing promising results. Information from November shows when patients take the treatment with chemotherapy, it helped patients survive a minimum of 18.2 months. The median overall survival was four months better in the experimental group compared to the control group. Targovax, the maker of the treatment, believes that it…
Read MorePeritoneal Mesothelioma Surgery with More organ Removal Can Help Survival
Mesothelioma surgery that removes more of an organ has been found to extend the survival of patients. It also did not increase the chance of severe complications nor did it change the survival benefits of aggressive surgery on patients with peritoneal mesothelioma. The complex surgery also did not negatively affect long term survival outcomes. This…
Read MoreMesothelioma Symptom Management Tool Links Doctors and Patients with a Smartphone
A study looking at a system that connects doctors and patients with a smartphone is showing that it could make the management of mesothelioma symptoms easier. Mesothelioma is a fast growing and aggressive cancer that has many different physical symptoms. Researchers in the United Kingdom are looking at a mesothelioma specific symptom management system. The…
Read MoreThe Herpes Virus is Being Tested as a Mesothelioma Treatment
An altered herpes virus is being tested in mesothelioma patients, and the results show that it can stabilize the growth of mesothelioma tumors. Half of the patients given the virus responded to the treatment, which is very promising. Thirteen patients were injected with a version of HSV (herpes causing virus) that seeks out cancer cells.…
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