Tomotherapy Treatment for Mesothelioma

June 23, 2014

Primary Outcome Measure:

Quality of Life [ Time Frame: 6 months ] [Designated as safety issue: Yes] Disease-specific symptom control rate post-treatment, based on Palliation Index [7].

Secondary Outcome Measures:

Breathing Function [ Time Frame: 6 months ] [ Designated as safety issue: Yes ] Pulmonary function test results at 1, 3 and 6 months post treatment
Survival/Response Rate [ Time Frame: 6 months ] [ Designated as safety issue: Yes ] performance status at 1, 3 and 6 months post treatment; and overall survival

Eligibility Criteria

Inclusion Criteria:
Histologic mesothelioma Refused/ineligible for surgery or chemotherapy Life expectancy >3 months
Exclusion Criteria:
Contraindications to thoracic radiotherapy Unable to lie flat for duration of radiation therapy

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